The IAF's largest transport plane. The 707 was developed in the early 1950's as a transport and refueling plane for the US Navy. Its service in the IAF began in the Yom Kippur War, during which it was used for flying armed personnel to Refidim and other airfields in the Sinai. After the war, several planes were purchased from TWA and other airlines, and additional 707s were leased from the Israel Aircraft Industries.

The Boeing-707 is considered to be a highly capable heavy-duty transport. It has four engines, can carry 82 tons of fuel and remain airborne for ten straight hours. Besides carrying passengers, the Boeing-707s have some additional roles in the IAF. One 707, for example, serves the Israeli Prime Minister and the President on their state visits abroad.

From 1983 on, the Boeings began to carry out midair refueling of fighters, thus lengthening the IAF's range. Their ability as refuellers exceeds even that of the Hercules.

The Re'em participated in several of the IAF's long range strikes, including the raid on PLO headquarters in Tunis. In 1991 six of the planes took part in Operation Shlomo, for bringing Ethiopian Jews to Israel.